Fierce clashes flared for a fourth day Tuesday in Syria’s commercial capital of Aleppo, showing the resilience of a rebel assault on regime targets.

President Barack Obama warned Syria against using its chemical weapons after Damascus acknowledged for the first time on Monday that they possessed such weapons and threatened to use them against any “foreign aggression.”

The state news agency said regime forces fought with rebels in the Aleppo neighborhoods of Salaheddine and Sukkari and claimed they had inflicted heavy losses. The Britain-based Syria Observatory, meanwhile, reported heavy fighting after midnight in several other neighborhoods as well as shelling by regime forces.

Some areas also saw protests calling for the fall of the government early in the morning, the Observatory reported.

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